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TN-10 safety: adverse events1

T1D Illustration

*Drug-related, mechanism-related, and expected findings that recover without clinical intervention.

- Blood/bone marrow: drop in white blood cell counts as they transiently attach to blood vessels

- Dermatology/skin: mild rash that resolves without intervention

1. Herold KC, Bundy BN, Long SA, et al; for Type 1 Diabetes TrialNet Study Group. An anti-CD3 antibody, teplizumab, in relatives at risk for type 1 diabetes. N Engl J Med. 2019;381(7):603-613.